Prognostic significance of proliferating cell nuclear antigen expression in colorectal cancer.

@article{AlSheneber1993PrognosticSO,
  title={Prognostic significance of proliferating cell nuclear antigen expression in colorectal cancer.},
  author={Ibrahim F Al-Sheneber and H R Shibata and John S Sampalis and Serge Jothy},
  journal={Cancer},
  year={1993},
  volume={71 6},
  pages={1954-9}
}
BACKGROUND Recognition of a biologic marker in colorectal cancer tissue that correlates with recurrence and poor survival would offer a rationale for planning aggressive adjuvant therapy. This study assessed the prognostic significance of proliferation activity in cancer cells and nonneoplastic epithelial cells in patients with colorectal cancer, using proliferating cell nuclear antigen (PCNA) immunohistochemical analysis. METHODS A mouse monoclonal antibody that reacted with PCNA was used to… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…