Prognostic significance of plasma cell propidium iodide and annexin-V indices and their mutual ratio in multiple myeloma.

@article{udla2006PrognosticSO,
  title={Prognostic significance of plasma cell propidium iodide and annexin-V indices and their mutual ratio in multiple myeloma.},
  author={Vlastimil {\vS}{\vc}udla and Marta Ordeltov{\'a} and Jiri Minarik and Ladislav Du{\vs}ek and Mark{\'e}ta Zemanov{\'a} and Jaroslav Ba{\vc}ovsk{\'y}},
  journal={Neoplasma},
  year={2006},
  volume={53 3},
  pages={
          213-8
        }
}
The aim of this study was a contemporaneous measurement of plasma cells proliferative and apoptotic activity in patients examined at the time of multiple myeloma (MM) diagnosis before initiation of chemotherapy, focussed on the following aspects: determination of prognostic significance of plasma cell propidium iodide (PC-PI) and annexin-V FITC (PC-AI) indices; optimal cut off of PC-PI and PC-AI with regard to overall survival; calculation of summary kinetic index of plasma cells (PC-PI/AI… CONTINUE READING