Prognostic significance of myocardial fibrosis quantification by histopathology and magnetic resonance imaging in patients with severe aortic valve disease.

@article{Azevedo2010PrognosticSO,
  title={Prognostic significance of myocardial fibrosis quantification by histopathology and magnetic resonance imaging in patients with severe aortic valve disease.},
  author={Clerio Francisco de Azevedo and Marcelo Nigri and Maria de Lourdes Higuchi and Pablo Maria Alberto Pomerantzeff and Guilherme Sobreira Spina and Roney Orismar Sampaio and Fl{\'a}vio Tarasoutchi and Max Grinberg and Carlos E. Rochitte},
  journal={Journal of the American College of Cardiology},
  year={2010},
  volume={56 4},
  pages={278-87}
}
OBJECTIVES We sought to determine whether the quantitative assessment of myocardial fibrosis (MF), either by histopathology or by contrast-enhanced magnetic resonance imaging (ce-MRI), could help predict long-term survival after aortic valve replacement. BACKGROUND Severe aortic valve disease is characterized by progressive accumulation of interstitial MF. METHODS Fifty-four patients scheduled to undergo aortic valve replacement were examined by ce-MRI. Delayed-enhanced images were used for… CONTINUE READING
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