Prognostic significance of miR-23b in combination with P-gp, MRP and LRP/MVP expression in non-small cell lung cancer.

@article{Jankov2016PrognosticSO,
  title={Prognostic significance of miR-23b in combination with P-gp, MRP and LRP/MVP expression in non-small cell lung cancer.},
  author={M{\'a}ria Jan{\'i}kov{\'a} and Veronika Ži{\vz}kov{\'a} and Joseph Skarda and Gvantsa Kharaishvili and Lenka Radov{\'a} and Zdeněk Kol{\'a}ř},
  journal={Neoplasma},
  year={2016},
  volume={63 4},
  pages={
          576-87
        }
}
Recently, miR-23b has emerged as a promising new cancer biomarker but its role in lung cancer has not been established yet. Patients still do not respond well to available treatments, probably due to expression of multidrug resistance (MDR) proteins, such as P-gp, MRP and LRP/MVP. The aim of this study was to determine the role of miR-23b in non-small cell lung cancer (NSCLC) and its relationship to the patient outcome together with MDR transporter proteins. We immunohistochemically evaluated… CONTINUE READING

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…