Prognostic significance of maximum primary tumor diameter in nasopharyngeal carcinoma

@article{Liang2012PrognosticSO,
  title={Prognostic significance of maximum primary tumor diameter in nasopharyngeal carcinoma},
  author={Shaobo Liang and Yan-ming Deng and Ning Zhang and Rui-liang Lu and Hai Zhao and Haiyang Chen and Shao-en Li and Dong-sheng Liu and Yong Chen},
  journal={BMC Cancer},
  year={2012},
  volume={13},
  pages={260 - 260}
}
BackgroundTo evaluate the prognostic value of maximum primary tumor diameter (MPTD) in nasopharyngeal carcinoma (NPC).MethodsThree hundred and thirty-three consecutive, newly-diagnosed NPC patients were retrospectively reviewed. Kaplan-Meier analysis and the log-rank test were used to estimate overall survival (OS), failure-free survival (FFS), distant metastasis-free survival (DMFS) and local relapse-free survival (LRFS). Cox proportional hazards regression analysis was used to assess the… 
Is maximum primary tumor diameter still a prognostic factor in patients with nasopharyngeal carcinoma treated using intensity-modulated radiotherapy?
TLDR
MPTD was an independent prognostic factor in patients with NPC treated using IMRT, and significantly improved the prognostic value of the current T classification criteria for NPC.
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PT regression speed at the end of RT was an independent prognostic factor of OS, FFS, and DMFS in NPC patients and immediate strengthening treatment may be provided to patients with poor tumor regression at the start of RT.
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Nasopharyngeal carcinoma with paranasal sinus invasion: the prognostic significance and the evidence-based study basis of its T-staging category according to the AJCC staging system
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Recommendations for Updating T and N Staging Systems for Nasopharyngeal Carcinoma in the Era of Intensity-Modulated Radiotherapy
TLDR
In the modern era of intensity-modulated radiotherapy, the staging system should be updated by down-staging the current stage T2 to T1, and it might be rational to merge subcategories N1 and N2.
Unidimensional measurement may be superior to assess primary tumor response after neoadjuvant chemotherapy for nasopharyngeal carcinoma
TLDR
Comparison of unidimensional measurements on magnetic resonance images in alternative planes for measurement of tumor response after neoadjuvant chemotherapy in patients with locally advanced nasopharyngeal carcinoma found axial UDM showed better correlation with volumetric measurements than axial BDM, and coronal U DM showed high correlation to VM.
Usefulness of Hybrid PET/MRI in Clinical Evaluation of Head and Neck Cancer Patients
TLDR
Hybrid PET/MR imaging is characterized by better agreement in T staging, higher specificity, sensitivity, PPV and NPV of lymph nodes evaluation than CT imaging, and is useful in preoperative staging of HNC.
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