Prognostic significance of lymphatic invasion in lymph node-positive breast carcinoma: findings from a large case series with long-term follow-up using immunohistochemical endothelial marker

@article{Mohammed2014PrognosticSO,
  title={Prognostic significance of lymphatic invasion in lymph node-positive breast carcinoma: findings from a large case series with long-term follow-up using immunohistochemical endothelial marker},
  author={Rabab AA Mohammed and Sindhu Menon and Stewart G Martin and Andrew R. Green and E. Claire Paish and Ian O. Ellis},
  journal={Modern Pathology},
  year={2014},
  volume={27},
  pages={1568-1577}
}
The poor prognostic significance of lymphatic invasion (LI) in breast carcinoma (BC) as a whole and in lymph node (LN)-negative patients in particular has been recognized in several studies; however, its prognostic role in LN-positive patients is still questionable. Aim of the current study was to assess prognostic role of LI in LN-positive BC specimens. Sections from non-selected 557 LN-positive BC specimens were stained with antibody to podoplanin/D2-40. LI was identified and correlated with… CONTINUE READING
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