Prognostic significance of leukopenia at the time of diagnosis in acute myeloid leukemia.

@article{Arellano2011PrognosticSO,
  title={Prognostic significance of leukopenia at the time of diagnosis in acute myeloid leukemia.},
  author={Martha Arellano and Leon Bernal-Mizrachi and Lin Pan and Mourad Tighiouart and Liliana P Souza and Xiangxue Guo and Morgan L. McLemore and Lisa Lima and Susan Sunay and Leonard T. Heffner and Zhengjia Chen and Georgia Zhou Chen and Amelia Nan Langston and Elliott F. Winton and Hanna J Khoury},
  journal={Clinical lymphoma, myeloma & leukemia},
  year={2011},
  volume={11 5},
  pages={
          427-32
        }
}
We investigated the clinical significance of leukopenia at the time of diagnosis in a cohort of 225 patients with newly diagnosed acute myeloid leukemia (AML) at a single institution. Leukocyte count was treated as a continuous variable and, using a receiver operating characteristic curve (ROC), a cutoff of 3,600/μL had the best sensitivity and specificity for remission (complete remission [CR]), relapse-free survival [RFS], and overall survival [OS]). In a multivariable model, leukopenia at… CONTINUE READING
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