Prognostic significance of lactate/proton symporters MCT1, MCT4, and their chaperone CD147 expressions in urothelial carcinoma of the bladder.

@article{Choi2014PrognosticSO,
  title={Prognostic significance of lactate/proton symporters MCT1, MCT4, and their chaperone CD147 expressions in urothelial carcinoma of the bladder.},
  author={Jung-Woo Choi and Young-Sik Kim and Jae-hong Lee},
  journal={Urology},
  year={2014},
  volume={84 1},
  pages={245.e9-15}
}
OBJECTIVE To investigate the prognostic significance of lactate/proton monocarboxylate transporters MCT1, MCT4, and their chaperone CD147 expressions in urothelial carcinoma of the bladder (UCB). METHODS We examined the expressions of MCT1, MCT4, and CD147 proteins in a total of 360 cases of UCB by immunohistochemistry. The immunohistochemical expressions were quantified using an ImageJ-based analysis program. RESULTS MCT1, MCT4, and CD147 expressions were increased in 130 (36.1%), 168 (46… CONTINUE READING
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