Prognostic significance of insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5 expression in breast cancer.

@article{Mita2007PrognosticSO,
  title={Prognostic significance of insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5 expression in breast cancer.},
  author={Keiko Mita and Zhenhuan Zhang and Y Ando and Tatsuya Toyama and Maho Hamaguchi and Shunzo Kobayashi and Shin-ichi Hayashi and Yoshitaka Fujii and Hirotaka Iwase and Hiroko Yamashita},
  journal={Japanese journal of clinical oncology},
  year={2007},
  volume={37 8},
  pages={575-82}
}
BACKGROUND Expression of estrogen-regulated genes has been considered as potential predictive markers for endocrine therapy. We focused on two insulin-like growth factor binding proteins (IGFBPs): IGFBP-4, which is an early-responsive estrogen-induced gene, and IGFBP-5, which is an estrogen-repressed gene. Investigation of IGFBP-4 and IGFBP-5 expression would provide important information for predicting prognosis and endocrine responsiveness. METHODS The levels of IGFBP-4 and IGFBP-5 mRNA… CONTINUE READING

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Tamoxifen failure in breast cancer: use of gene expression array and immunohistochemistry tissue micro arrays to define a molecular signature of tamoxifen resistance

  • SE Bray, K Robertson, J Vendrell, C Nguyen, CA Purdie, G Thomson
  • Breast Cancer Res Treat
  • 2005
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