Prognostic significance of histopathologic response to chemotherapy in nonmetastatic Ewing's sarcoma of the extremities.

@article{Picci1993PrognosticSO,
  title={Prognostic significance of histopathologic response to chemotherapy in nonmetastatic Ewing's sarcoma of the extremities.},
  author={Piero Picci and Bruce T. Rougraff and Gaetano Bacci and James R. Neff and Luca Sangiorgi and Alberto Cazzola and Nicola Baldini and Stefano Ferrari and M. Cristina Mercuri and Pietro Ruggieri},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1993},
  volume={11 9},
  pages={1763-9}
}
PURPOSE To evaluate more accurately the effectiveness of preoperative chemotherapy in the treatment of patients with Ewing's sarcoma, we studied histopathologically the chemotherapeutic response and correlated it to oncologic outcome. PATIENTS AND METHODS Between June 1983 and December 1989, 68 patients with nonmetastatic Ewing's sarcoma of the extremities were treated at our institute with preoperative chemotherapy (without radiation therapy) and surgery. The specimens were retrospectively… CONTINUE READING

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