Prognostic significance of heat shock protein-27 expression in hepatocellular carcinoma and its relation to histologic grading and survival.

@article{King2000PrognosticSO,
  title={Prognostic significance of heat shock protein-27 expression in hepatocellular carcinoma and its relation to histologic grading and survival.},
  author={K L King and Anna F-Y. Li and G Y Chau and C. W. Chi and Chung Wah Wu and Chen Lung Huang and W. Y. Lui},
  journal={Cancer},
  year={2000},
  volume={88 11},
  pages={2464-70}
}
BACKGROUND The expression of heat shock protein-27 (HSP-27) has been detected in some human tumors. In this study the authors investigated HSP-27 expression in patients with hepatocellular carcinoma (HCC) and examined its prognostic significance. METHODS Expression of HSP-27 was studied in 58 HCC and adjacent noncancerous liver tissues by immunohistochemical stain. The relation between its expression and eight known prognostic factors was evaluated. RESULTS Of the 58 HCC tissues studied… CONTINUE READING

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