Prognostic significance of free radicals: mediated injury occurring in the kidney donor.

@article{Kosieradzki2003PrognosticSO,
  title={Prognostic significance of free radicals: mediated injury occurring in the kidney donor.},
  author={Maciej Kosieradzki and Julita Kuczyńska and Jadwiga Piwowarska and Irena Wegrowicz-Rebandel and Artur Kwiatkowski and Wojciech Lisik and Grzegorz Michalak and Roman Danielewicz and Leszek Paczek and Wojciech A Rowinski},
  journal={Transplantation},
  year={2003},
  volume={75 8},
  pages={
          1221-7
        }
}
BACKGROUND Brain death is associated with hemodynamic disturbances in systemic circulation and metabolic storm, and, thus, free radical-mediated injury to donor tissues was hypothesized. An assessment of oxidative stress in the donor and its effect on posttransplant kidney graft function comprised the scope of the study. METHODS A prospective study was performed in 27 donors and 50 kidney transplant recipients. Sera from 27 brain-dead organ donors and preservation media were tested for… CONTINUE READING
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