Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer.

@article{Wright2000PrognosticSO,
  title={Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer.},
  author={Caroline M Wright and O F Dent and Melissa L Barker and Ronald C. Newland and Pierre H. Chapuis and E. Leslie Bokey and Joanne P. Young and Barbara A. Leggett and Jeremy R. Jass and Graeme A. Macdonald},
  journal={The British journal of surgery},
  year={2000},
  volume={87 9},
  pages={1197-202}
}
BACKGROUND Colorectal cancers exhibiting microsatellite instability (MSI) appear to have unique biological behaviour. This study analyses the association between extensive MSI (MSI-H), clinicopathological features and survival in an unselected group of patients with sporadic Australian Clinico-Pathological Stage (ACPS) C (tumour node metastasis stage III) colorectal cancer. METHODS Some 255 patients who underwent resection for sporadic ACPS C colorectal cancer between 1986 and 1992 were… CONTINUE READING

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