Prognostic significance of circulating tumour cells enumerated after filtration enrichment in early and metastatic breast cancer patients

@article{Wong2006PrognosticSO,
  title={Prognostic significance of circulating tumour cells enumerated after filtration enrichment in early and metastatic breast cancer patients},
  author={Nan Soon Wong and H. J. Kahn and Liying Zhang and Stephanie Oldfield and Lillian M. J. Yang and Alexander N Marks and Maureen Elizabeth Trudeau},
  journal={Breast Cancer Research and Treatment},
  year={2006},
  volume={99},
  pages={63-69}
}
We previously found a higher incidence of circulating tumour cells (CTCs) in women with metastatic breast cancer compared to early disease. In this study, we present follow-up data to explore the prognostic significance of these findings. CTCs were quantified by immunostaining and direct visualization after centrifugation and filtration enrichment of peripheral blood from 131 patients. Time to progression (TTP) and overall survival (OS) were defined as interval from first blood sampling to… CONTINUE READING
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