Prognostic significance of chromosome 3 alterations determined by microsatellite analysis in uveal melanoma: a long-term follow-up study

@inproceedings{Thomas2012PrognosticSO,
  title={Prognostic significance of chromosome 3 alterations determined by microsatellite analysis in uveal melanoma: a long-term follow-up study},
  author={Sabrena Thomas and Carolin P{\"u}tter and Sharon H Weber and Norbert Bornfeld and Dietmar Rudolf Lohmann and Michael Zeschnigk},
  booktitle={British Journal of Cancer},
  year={2012}
}
Background:In uveal melanoma (UM), the most frequent primary intraocular tumour in adults, loss of one entire chromosome 3 (monosomy 3 (M3)) is observed in ∼50% of tumours and is significantly associated with metastatic disease. The strong association of metastatic disease with M3 offers the opportunity for molecular prognostic testing of UM patients.Methods:To re-evaluate M3 as prognostic marker in our clinical and laboratory setting and to determine the metastatic potential of rare tumours… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 22 references

Proportional hazards tests and diagnostics based on weighted residuals

  • P Grambsch, T Therneau
  • Biometrika 81:
  • 1994
Highly Influential
2 Excerpts

Similar Papers

Loading similar papers…