Prognostic significance of bone invasion for oral cavity squamous cell carcinoma considered T1/T2 by American joint committee on cancer size criteria.

@article{Fried2014PrognosticSO,
  title={Prognostic significance of bone invasion for oral cavity squamous cell carcinoma considered T1/T2 by American joint committee on cancer size criteria.},
  author={David V. Fried and Brandon T Mullins and Mark Weissler and Carol D Shores and Adam M. Zanation and Trevor Hackman and William B. Shockley and Neil Hayes and Bhishamjit S. Chera},
  journal={Head & neck},
  year={2014},
  volume={36 6},
  pages={776-81}
}
BACKGROUND It is unclear whether bone invasion in small oral cavity squamous cell carcinomas (OCSCC) results in worse prognosis. METHODS Two hundred fifty-four patients with OCSCC were identified and divided into 3 cohorts: (1) ≤4 cm with no bone invasion; (2) ≤4 cm with bone invasion; and (3) ≥4 cm or other factors (eg, skin invasion, deep muscle invasion) that would qualify for American Joint Committee on Cancer (AJCC) T4 classification aside from bone invasion. Depth of bone invasion (none… CONTINUE READING
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