Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling

@inproceedings{Liu2016PrognosticSO,
  title={Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling},
  author={Hongda Liu and Qun Zhang and Kangshuai Li and Zheng Gong and Zhaochen Liu and Yunfei Xu and Mary Hannah Swaney and Kunhong Xiao and Yuxin Chen},
  booktitle={Oncotarget},
  year={2016}
}
Patients with liver metastases of colorectal cancer (CRCLM) have a poorer prognosis compared to colorectal cancer (CRC) patients in local stage. Evaluating the recurrence and overall survival of advanced patients is critical in improving disease treatment and clinical outcome. Here we investigated the expression pattern of USP33, a deubiquitinating enzyme, in both primary CRC tissues and liver metastases tissues. Univariate and multivariate analyses identified that low expression of USP33 in… CONTINUE READING
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