Prognostic significance of NDRG1 expression in oral and oropharyngeal squamous cell carcinoma

  title={Prognostic significance of NDRG1 expression in oral and oropharyngeal squamous cell carcinoma},
  author={Marcelo A. Santos and Ana Maria da Cunha Mercante and Fabio Daumas Nunes and A M Leopoldino and Marcos Brasilino de Carvalho and Diana Gazito and Rossana Ver{\'o}nica Mendoza L{\'o}pez and Paula Blandina Olga Chiappini and Paulo Bentes de Carvalho Neto and Erica Erina Fukuyama and Eloiza Helena Tajara and Iuri Drumond Louro and Adriana Madeira {\'A}lvares da Silva},
  journal={Molecular Biology Reports},
Human N-myc downstream-regulated gene 1 (NDRG1) is a metastasis suppressor gene with several potential functions, including cell differentiation, cell cycle regulation and response to hormones, nickel and stress. The purpose of this study was to investigate the immunoexpression of NDRG1 in oral and oropharyngeal squamous cell carcinomas searching for its role in the clinical course of these tumors. We investigated immunohistochemical expression of NDRG1 protein in 412 tissue microarray cores of… CONTINUE READING
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clinical perspectives

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  • 2012
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