Prognostic significance of Ki-67 labeling indices obtained using MIB-1 monoclonal antibody in patients with supratentorial astrocytomas.

@article{Wakimoto1996PrognosticSO,
  title={Prognostic significance of Ki-67 labeling indices obtained using MIB-1 monoclonal antibody in patients with supratentorial astrocytomas.},
  author={Hiroaki Wakimoto and Masaru Aoyagi and Toshimichi Nakayama and Goro Nagashima and Sohei Yamamoto and Masahiro Tamaki and Kosei Hirakawa},
  journal={Cancer},
  year={1996},
  volume={77 2},
  pages={373-80}
}
BACKGROUND Identification of the prognosis of patients with gliomas is important for selecting and evaluating the effectiveness of treatment. The aim of this study was to evaluate the Ki-67 labeling index (LI) using the newly generated MIB-1 monoclonal antibody (MoAb) as a prognostic indicator for patients with astrocytomas. METHODS Ki-67 immunohistochemistry was performed on paraffin sections to estimate the growth potential of 72 supratentorial astrocytomas using the MIB-1 MoAb after… CONTINUE READING

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