Prognostic significance of CXCL12 expression in patients with colorectal carcinoma.

  title={Prognostic significance of CXCL12 expression in patients with colorectal carcinoma.},
  author={Yuri Akishima-Fukasawa and Yukihiro Nakanishi and Yoshinori Ino and Yoshihiro Moriya and Yae Kanai and Setsuo Hirohashi},
  journal={American journal of clinical pathology},
  volume={132 2},
  pages={202-10; quiz 307}
The present study investigated the protein expression level of CXCL12 in colorectal cancer and aimed to elucidate its association with prognosis. CXCL12 positivity in 50% or more of tumor cells was defined as high expression and that in less than 50% of the tumor cells as low expression. CXCL12+ tumor budding at the invasive front was divided into 2 grades: high with 10 or more budding foci per x200 field of view and low grade with fewer than 10 budding foci. Patients with high expression (72.7… CONTINUE READING
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Clinical implication of CXCL12 expression in gastric cancer

  • S Ishigami, S Natsugoe, H Okumura
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  • 2007

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