Prognostic significance and interobserver variability of histologic grading systems for endometrial carcinoma.

@article{Scholten2004PrognosticSA,
  title={Prognostic significance and interobserver variability of histologic grading systems for endometrial carcinoma.},
  author={Astrid N. Scholten and Vincent T. H. B. M. Smit and Henk Beerman and Wim L J van Putten and Carien L. Creutzberg},
  journal={Cancer},
  year={2004},
  volume={100 4},
  pages={764-72}
}
BACKGROUND The most widely used histologic grading system for endometrial carcinoma is the three-tiered International Federation of Gynecology and Obstetrics (FIGO) system. Although FIGO grading has significant predictive value, the reproducibility of Grade 2 is limited. Recently, a binary grading system was proposed based on the amount of solid growth, the pattern of myometrial invasion, and the presence of tumor cell necrosis. The authors analyzed and compared the prognostic significance and… CONTINUE READING

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