Prognostic markers in cancer: the evolution of evidence from single studies to meta-analysis, and beyond

@article{Riley2009PrognosticMI,
  title={Prognostic markers in cancer: the evolution of evidence from single studies to meta-analysis, and beyond},
  author={Richard D Riley and Willi Sauerbrei and Douglas G. Altman},
  journal={British Journal of Cancer},
  year={2009},
  volume={100},
  pages={1219 - 1229}
}
In oncology, prognostic markers are clinical measures used to help elicit an individual patient's risk of a future outcome, such as recurrence of disease after primary treatment. They thus facilitate individual treatment choice and aid in patient counselling. Evidence-based results regarding prognostic markers are therefore very important to both clinicians and their patients. However, there is increasing awareness that prognostic marker studies have been neglected in the drive to improve… CONTINUE READING

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Systematic reviews of evaluations of prognostic variables

  • DG Altman
  • BMJ 323:
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