Prognostic indicators of changes in bone density measures in adolescent girls with anorexia nervosa-II.

  title={Prognostic indicators of changes in bone density measures in adolescent girls with anorexia nervosa-II.},
  author={Madhusmita Misra and Rajani Prabhakaran and Karen Klahr Miller and Mark Goldstein and Diane Mickley and Laura J Clauss and Patrice Lockhart and Jennalee J Cord and David B. Herzog and Debra K Katzman and Anne Klibanski},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={93 4},
INTRODUCTION Adolescents with anorexia nervosa (AN) have low bone mineral density (BMD). Baseline predictors of temporal BMD changes (DeltaBMD) in AN, including 1) gastrointestinal peptides regulating food intake and appetite that have been related to bone metabolism and 2) bone turnover markers, have not been well characterized. We hypothesized that baseline levels of nutritionally regulated hormones and of bone turnover markers would predict DeltaBMD overall. METHODS In a prospective… CONTINUE READING
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