Prognostic implications of leg ulcers from hydroxycarbamide therapy in patients with essential thrombocythaemia.

Abstract

Essential thrombocythemia (ET) is a clonal stem-cell disorder characterized by persistent thrombocytosis. Patients with ET and risk factors for thrombotic complications have been shown to benefit from cytoreductive therapy, the most common agent used being, hydroxycarbamide. Although this agent is usually well-tolerated, one of the recognized adverse… (More)
DOI: 10.1016/j.leukres.2011.11.017

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