Prognostic implication of the p53 protein and Ki-67 antigen immunohistochemistry in malignant fibrous histiocytoma.

@article{Yang1995PrognosticIO,
  title={Prognostic implication of the p53 protein and Ki-67 antigen immunohistochemistry in malignant fibrous histiocytoma.},
  author={Ping Yang and Takanori Hirose and Tadashi Hasegawa and Kunihiko Seki and Takaaki Sano and Kazuoki Hizawa},
  journal={Cancer},
  year={1995},
  volume={76 4},
  pages={618-25}
}
BACKGROUND Mounting evidence indicates that p53 regulates cell growth and abnormal p53 immunophenotypic expression is associated with an unfavorable prognosis for patients with some types of carcinoma. The prognostic significance of p53 overexpression in malignant fibrous histiocytomas (MFHs) of soft tissue has not yet been elucidated. METHODS Expressions of p53 protein and Ki-67 antigen in 54 primary MFHs of soft tissue were investigated immunohistochemically and indexed quantitatively by… CONTINUE READING
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