Prognostic implication of molecular aberrations in cytogenetically normal acute myeloid leukemia patients receiving allogeneic hematopoietic stem cell transplantation.

@article{Liu2013PrognosticIO,
  title={Prognostic implication of molecular aberrations in cytogenetically normal acute myeloid leukemia patients receiving allogeneic hematopoietic stem cell transplantation.},
  author={Yu-Chi Liu and H H Hsiao and P M Lin and W C Yang and Catherine S. Chang and Te Chih Liu and John F Hsu and Mi Yean Yang and S F Lin},
  journal={Genetics and molecular research : GMR},
  year={2013},
  volume={12 4},
  pages={5414-23}
}
Different molecular aberrations can be discriminated into certain prognostic subgroups in cytogenetically normal acute myeloid leukemia (CN-AML) patients but their impact on allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains controversial and studies from Asian populations are lacking. Forty-two adult non-M3 AML patients receiving allo-HSCT from 2002 to 2009 in southern Taiwan were retrospectively reviewed for survey, 23 (54.7%) of whom were CN-AML. NPM1, FLT3-ITD, and CEBPA… CONTINUE READING
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