Prognostic impacts of EGFR mutation status and subtype in patients with surgically resected lung adenocarcinoma.

@article{Takamochi2017PrognosticIO,
  title={Prognostic impacts of EGFR mutation status and subtype in patients with surgically resected lung adenocarcinoma.},
  author={Kazuya Takamochi and Shiaki Oh and Takeshi Matsunaga and Kenji Suzuki},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={2017},
  volume={154 5},
  pages={1768-1774.e1}
}
OBJECTIVE Epidermal growth factor receptor (EGFR) gene mutation status is a well-established predictor of the efficacy of EGFR tyrosine-kinase inhibitor (TKI) therapy in patients with non-small cell lung cancer. Recently, differences in EGFR mutation subtypes have been reported to be associated with the efficacy of EGFR-TKI therapy. The prognostic impact of EGFR mutation status and subtypes remains controversial, however. METHODS We retrospectively reviewed 939 patients with surgically… CONTINUE READING
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