Prognostic impact of programmed cell death 1 ligand 1 expression in human leukocyte antigen class I-positive hepatocellular carcinoma after curative hepatectomy

@article{Umemoto2014PrognosticIO,
  title={Prognostic impact of programmed cell death 1 ligand 1 expression in human leukocyte antigen class I-positive hepatocellular carcinoma after curative hepatectomy},
  author={Yuichiroh Umemoto and Shinji Okano and Yoshihiro Matsumoto and Hidekazu Nakagawara and Rumi Matono and Shohei Yoshiya and Yo-ichi Yamashita and Tomoharu Yoshizumi and Toru Ikegami and Yuji Soejima and Mamoru Harada and Shinichi Aishima and Yoshinao Oda and Ken Shirabe and Yoshihiko Maehara},
  journal={Journal of Gastroenterology},
  year={2014},
  volume={50},
  pages={65-75}
}
Hepatocellular carcinoma (HCC) is one of the most common solid tumors worldwide. Surgery is potentially curative, but high recurrence rates worsen patient prognosis. The interaction between the proteins programmed cell death 1 (PD-1) and programmed cell death 1 ligand 1 (PD-L1) is an important immune checkpoint. The significance of PD-L1 expression and… CONTINUE READING