Prognostic impact of circulating soluble LR11 on long-term clinical outcomes in patients with coronary artery disease.

@article{Ogita2016PrognosticIO,
  title={Prognostic impact of circulating soluble LR11 on long-term clinical outcomes in patients with coronary artery disease.},
  author={Manabu Ogita and Katsumi Miyauchi and Takatoshi Kasai and Shuta Tsuboi and Hideki Wada and Ryo Naito and Hirokazu Konishi and Tomotaka Dohi and Hiroshi Tamura and Shinya Okazaki and Naotake Yanagisawa and Kazunori Shimada and Satoru Suwa and Meizi Jiang and Hideaki Bujo and Hiroyuki Daida},
  journal={Atherosclerosis},
  year={2016},
  volume={244},
  pages={216-21}
}
BACKGROUND LR11, a member of LDL receptor family, is a novel marker of the proliferation of intimal smooth muscle cells (SMCs). LR11 is released in soluble form (sLR11) by proteolytic shedding and has biological activity toward SMC migration. We previously showed that circulating sLR11 positively correlates with carotid intima-medial thickness (IMT… CONTINUE READING