Prognostic genetic markers in malignant gliomas Prognostic genetic markers in malignant gliomas

@inproceedings{Ketter2010PrognosticGM,
  title={Prognostic genetic markers in malignant gliomas Prognostic genetic markers in malignant gliomas},
  author={Ralf Ketter and Silke Wemmert and Stefan Linsler and Wolf-Ingo Steudel and Steffi Urbschat},
  year={2010}
}
Glioblastomas are the most frequent and malignant brain tumors in adults. Surgical cure is virtually impossible and despite of radiation and chemotherapy the clinical course is very poor. Epigenetic silencing of MGMT has been associated with a better response to temozolomide-chemotherapy. We previously showed that temozolomide increases the median survival… CONTINUE READING