Prognostic factors in resectable pathological N2 disease of non-small cell lung cancer

@article{Hsieh2015PrognosticFI,
  title={Prognostic factors in resectable pathological N2 disease of non-small cell lung cancer},
  author={Chen-Ping Hsieh and Jui-Ying Fu and Yun-hen Liu and Cheng-Ta Yang and Ming-Ju Hsieh and Ying Huang Tsai and Yi-cheng Wu and Ching-Yang Wu},
  journal={Biomedical Journal},
  year={2015},
  volume={38},
  pages={329 - 335}
}
Background: N2-positive non-small cell lung cancer (NSCLC) exhibits extremely low survival rates. The role of surgery in operable locally advanced N2 NSCLC remains controversial. In this study, we tried to analyze the role of surgery in resectable N2 NSCLC and the relationship between survival and clinico-pathologic factors from a pathologic point of view. Methods: 108 resectable pathologic N2-positive NSCLC patients, diagnosed from January 2005 to July 2012, were enrolled in this study. We… 

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References

SHOWING 1-10 OF 43 REFERENCES
Factors determining survival in resected N2 lung cancer.
Treatment strategy for patients with surgically discovered N2 stage IIIA non-small cell lung cancer.
Value of the Metastatic Lymph Node Ratio for Predicting the Prognosis of Non-Small-Cell Lung Cancer Patients
TLDR
The combination of the LNR and pN status provides a valuable help with prognosis and could efficiently predicted outcomes of patients with lymph node-positive NSCLC.
Skip metastases: analysis of their clinical significance and prognosis in the IIIA stage of non-small cell lung cancer.
The importance of surgery to non-small cell carcinoma of lung with mediastinal lymph node metastasis.
Intra-tumoral vascular or perineural invasion as prognostic factors for long-term survival in early stage non-small cell lung carcinoma.
...
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