Prognostic factors in patients presenting with severe neurological forms of Wilson's disease.

@article{Prashanth2005PrognosticFI,
  title={Prognostic factors in patients presenting with severe neurological forms of Wilson's disease.},
  author={Lingappa Kumar Prashanth and Arun B. Taly and Sanjib Sinha and Shivashankar Ravishankar and Gujjar R Arunodaya and Mandapati K Vasudev and H. Satyanarayana Swamy},
  journal={QJM : monthly journal of the Association of Physicians},
  year={2005},
  volume={98 8},
  pages={557-63}
}
BACKGROUND Wilson's disease (WD), a metabolic disorder, is believed to be potentially reversible, even in its severe form. However, some patients do not respond to treatment. AIM To analyse prognostic factors in severe WD. DESIGN Retrospective audit. METHODS A total of 140 patients were regularly followed from February 2002 to May 2004. Twenty-nine (18 males, 11 females) had severe disease, as defined by Modified Schwab and England Activities of Daily Living score (MSEADL) of < or=50% or… CONTINUE READING