Prognostic factors for the course of functional status of patients with ALS: a systematic review

@article{Creemers2014PrognosticFF,
  title={Prognostic factors for the course of functional status of patients with ALS: a systematic review},
  author={Huub Creemers and Hepke F. Grupstra and Frans Nollet and Leonard H. van den Berg and Anita Beelen},
  journal={Journal of Neurology},
  year={2014},
  volume={262},
  pages={1407-1423}
}
The progressive course of amyotrophic lateral sclerosis (ALS) results in an ever-changing spectrum of the care needs of patients with ALS. Knowledge of prognostic factors for the functional course of ALS may enhance clinical prediction and improve the timing of appropriate interventions. Our objective was to systematically review the evidence regarding prognostic factors for the rate of functional decline of patients with ALS, assessed with versions of the ALS Functional Rating Scale (ALSFRS… 

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