Prognostic factors for survival in patients treated in phase I clinical trials.

@article{Janisch1994PrognosticFF,
  title={Prognostic factors for survival in patients treated in phase I clinical trials.},
  author={Linda Janisch and Rosemarie Mick and Richard L. Schilsky and Nicholas John Vogelzang and Susan O'brien and Mustafa Sinan Kut and Mark J. Ratain},
  journal={Cancer},
  year={1994},
  volume={74 7},
  pages={1965-73}
}
BACKGROUND Patients with advanced or metastatic cancer treated in Phase I clinical trials are considered to have a poor prognosis. Survival from first treatment in a Phase I trial was determined for 349 patients. Univariate and multivariate survival analyses were performed to determine whether potential prognostic factors and distinct risk groups could be identified. METHODS Patients were identified retrospectively from a large data base of patients with advanced or metastatic cancer treated… CONTINUE READING