Prognostic factors for chronic active Epstein-Barr virus infection.

  title={Prognostic factors for chronic active Epstein-Barr virus infection.},
  author={Hiroshi Kimura and Tsuneo Morishima and Hirokazu Kanegane and Shouichi Ohga and Yo Hoshino and Akihiko Maeda and Shosuke Imai and Motohiko Okano and Tomohiro Morio and Shunpei Yokota and Shigeru Tsuchiya and Akihiro Yachie and Shinsaku Imashuku and Keisei Kawa and Hiroshi Wakiguchi},
  journal={The Journal of infectious diseases},
  volume={187 4},
Chronic active Epstein-Barr virus infection (CAEBV) is a high-mortality and high-morbidity disease. To clarify the prognostic factors, a national survey was performed in Japan, and data for 82 patients who met the criteria for CAEBV were analyzed. Of these 82 patients, 47 were alive and 35 had already died. Multivariate analysis revealed that thromobocytopenia and age at disease onset were correlated with mortality. The probability of 5-year survival was 0.45 for older patients (onset age, > or… CONTINUE READING