Prognostic effect of intratumoral neutrophils across histological subtypes of non-small cell lung cancer

@inproceedings{Rakaee2016PrognosticEO,
  title={Prognostic effect of intratumoral neutrophils across histological subtypes of non-small cell lung cancer},
  author={Mehrdad Rakaee and L T Busund and Erna-Elise Paulsen and Elin Richardsen and Samer Al-Saad and Sigve Andersen and Tom Donnem and Roy Martin Bremnes and Thomas Karsten Kilvaer},
  booktitle={Oncotarget},
  year={2016}
}
Recent data indicate that tumor-associated neutrophils (TANs) serve a dual role in tumor progression and regression. CD66b is a neutrophil marker and has been associated with patient outcome in various cancers. However, its clinical impact in non-small cell lung cancer (NSCLC) remains controversial. 536 NSCLC patients, of which 172 harbored lymph node metastases, were included in this study. Tissue microarrays were constructed and multiplexed immunohistochemistry of CD66b, CD34 and pan-keratin… CONTINUE READING
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