Prognostic and predictive markers in medullary thyroid carcinoma.

@article{Erovic2012PrognosticAP,
  title={Prognostic and predictive markers in medullary thyroid carcinoma.},
  author={Boban M. Erovic and Dae Kim and Clarissa A Cassol and D Goldstein and Jonathan C. Irish and Sylvia L Asa and Ozgur Mete},
  journal={Endocrine pathology},
  year={2012},
  volume={23 4},
  pages={232-42}
}
Unlike papillary thyroid carcinoma, medullary thyroid carcinoma is insensitive to adjuvant treatment with radioactive iodine. The clinical management of patients with advanced or metastatic disease remains challenging since no effective systemic adjuvant therapy is available. We aimed to identify markers of aggressive disease and novel drugable protein targets that would provide systemic adjuvant treatment for patients with advanced medullary thyroid carcinoma. We therefore examined morphologic… CONTINUE READING

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