Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury.

@article{Ware2010PrognosticAP,
  title={Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury.},
  author={Lorraine B. Ware and Tatsuki Koyama and Dean Billheimer and William C H Wu and Gordon R. Bernard and Boyd Taylor Thompson and Roy G. Brower and Theodore J Standiford and Thomas R. Martin and Michael A. Matthay},
  journal={Chest},
  year={2010},
  volume={137 2},
  pages={288-96}
}
BACKGROUND No single clinical or biologic marker reliably predicts clinical outcomes in acute lung injury (ALI)/ARDS. We hypothesized that a combination of biologic and clinical markers would be superior to either biomarkers or clinical factors alone in predicting ALI/ARDS mortality and would provide insight into the pathogenesis of clinical ALI/ARDS. METHODS Eight biologic markers that reflect endothelial and epithelial injury, inflammation, and coagulation (von Willebrand factor antigen… CONTINUE READING
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Combining clinical and biochemical indices improves prediction of outcomes in acute lung injury [ abstract ]

  • LB Ware, D Billheimer, PE Parsons
  • Am J Respir Crit Care Med
  • 2007

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