Prognostic and Predictive Relevance of DNAM-1, SOCS6 and CADH-7 Genes on Chromosome 18q in Colorectal Cancer

@article{Storojeva2005PrognosticAP,
  title={Prognostic and Predictive Relevance of DNAM-1, SOCS6 and CADH-7 Genes on Chromosome 18q in Colorectal Cancer},
  author={Iana Storojeva and J. Boulay and P. Ballabeni and M. Buess and L. Terracciano and U. Laffer and G. Mild and R. Herrmann and C. Rochlitz},
  journal={Oncology},
  year={2005},
  volume={68},
  pages={246 - 255}
}
  • Iana Storojeva, J. Boulay, +6 authors C. Rochlitz
  • Published 2005
  • Medicine
  • Oncology
    • Purpose: Chromosome 18q deletion has been described as a negative prognostic factor in colorectal cancer (CRC). The relationship between its supposed negative prognostic influence and the inactivation of candidate tumor suppressors deleted in colorectal cancer, Smad2 and Smad4 has not been definitively established. The aim of the present study was to evaluate the genetic status of three novel putative tumor suppressors, Cadh-7, DNAX accessory molecule-1 (Dnam-1) and suppressor of cytokine… CONTINUE READING
    View on PubMed
    doi.org
    24 Citations
    Highly Influencial Citations
    1
    Background Citations
    10
    Results Citations
    2
    24 Citations
    Citation Type

    Citation Type

    Suppressor of Cytokine Signaling 4 Detected as a Novel Gastric Cancer Suppressor Gene using Double Combination Array Analysis
    • 23
    Expression of SOCSs in human prostate cancer and their association in prognosis
    • 30
    Chromosomal changes characterize head and neck cancer with poor prognosis
    • 38
    Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer
    • 37
    • Highly Influenced
    • PDF
    The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome.
    • 6
    • PDF
    Reduced expression of SOCS2 and SOCS6 in hepatocellular carcinoma correlates with aggressive tumor progression and poor prognosis
    • 41
    Molecular biomarkers in colorectal carcinoma.
    • 9
    Long noncoding RNA TUSC7 inhibits cell proliferation, migration and invasion by regulating SOCS4 (SOCS5) expression through targeting miR-616 in endometrial carcinoma.
    • 4
    Clinical, biological, and molecular aspects of metastasis in colorectal cancer.
    • U. Stein, P. Schlag
    • Medicine
    • Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer
    • 2007
    • 91
    Somatic gene copy number alterations in colorectal cancer: new quest for cancer drivers and biomarkers
    • 61

    References

    SHOWING 1-10 OF 51 REFERENCES
    Prognostic significance of allelic lost at chromosome 18q21 for stage II colorectal cancer.
    • 139
    Survival and acquired genetic alterations in colorectal cancer.
    • 112
    Confirmation that chromosome 18q allelic loss in colon cancer is a prognostic indicator.
    • 152
    SMAD7 is a prognostic marker in patients with colorectal cancer
    • 81
    Molecular predictors of survival after adjuvant chemotherapy for colon cancer.
    • 830
    Loss of heterozygosity at 18q21 is indicative of recurrence and therefore poor prognosis in a subset of colorectal cancers
    • 71
    • PDF
    Allelic loss on chromosome 18q as a prognostic marker in stage II colorectal cancer.
    • 154
    Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers.
    • 370
    • PDF
    Allelic loss of chromosome 18q and prognosis in colorectal cancer.
    • 701
    Quantification of MYCN, DDX1, and NAG Gene Copy Number in Neuroblastoma Using a Real-Time Quantitative PCR Assay
    • 176
    • PDF