Prognostic and Predictive Relevance of DNAM-1, SOCS6 and CADH-7 Genes on Chromosome 18q in Colorectal Cancer

  title={Prognostic and Predictive Relevance of DNAM-1, SOCS6 and CADH-7 Genes on Chromosome 18q in Colorectal Cancer},
  author={Iana Storojeva and J. Boulay and P. Ballabeni and M. Buess and L. Terracciano and U. Laffer and G. Mild and R. Herrmann and C. Rochlitz},
  pages={246 - 255}
  • Iana Storojeva, J. Boulay, +6 authors C. Rochlitz
  • Published 2005
  • Medicine
  • Oncology
  • Purpose: Chromosome 18q deletion has been described as a negative prognostic factor in colorectal cancer (CRC). The relationship between its supposed negative prognostic influence and the inactivation of candidate tumor suppressors deleted in colorectal cancer, Smad2 and Smad4 has not been definitively established. The aim of the present study was to evaluate the genetic status of three novel putative tumor suppressors, Cadh-7, DNAX accessory molecule-1 (Dnam-1) and suppressor of cytokine… CONTINUE READING
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