Prognostic Value of Tubulointerstitial Lesions, Urinary N-Acetyl-β-d-Glucosaminidase, and Urinary β2-Microglobulin in Patients with Type 2 Diabetes and Biopsy-Proven Diabetic Nephropathy.

@article{Mise2016PrognosticVO,
  title={Prognostic Value of Tubulointerstitial Lesions, Urinary N-Acetyl-β-d-Glucosaminidase, and Urinary β2-Microglobulin in Patients with Type 2 Diabetes and Biopsy-Proven Diabetic Nephropathy.},
  author={Koki Mise and Junichi Hoshino and Toshiharu Ueno and Ryo Hazue and Jumpei Hasegawa and Akinari Sekine and Keiichi Sumida and Rikako Hiramatsu and Eiko Hasegawa and Masayuki Yamanouchi and Noriko Hayami and Tatsuya Suwabe and Naoki Sawa and Takeshi Fujii and Shigeko Hara and Kenichi Ohashi and Kenmei Takaichi and Yoshifumi Ubara},
  journal={Clinical journal of the American Society of Nephrology : CJASN},
  year={2016},
  volume={11 4},
  pages={593-601}
}
BACKGROUND AND OBJECTIVES Some biomarkers of renal tubular injury are reported to be useful for predicting renal prognosis in the early stage of diabetic nephropathy (DN). Our study compared predictions of the renal prognosis by such biomarkers and by histologic tubulointerstitial damage. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Among 210 patients with type 2 diabetes and biopsy-proven DN managed from 1985 to 2011, 149 patients with urinary N-acetyl-β-d-glucosaminidase (NAG) and urinary… CONTINUE READING