Prognostic Value of QT/RR Slope in Predicting Mortality in Patients with Congestive Heart Failure

@article{Cygankiewicz2008PrognosticVO,
  title={Prognostic Value of QT/RR Slope in Predicting Mortality in Patients with Congestive Heart Failure},
  author={Iwona Cygankiewicz and Wojciech Zareba and Rafael Ricardo Valdez Vazquez and Jesus Almendral and Antoni Bay{\'e}s‐Gen{\'i}s and Miquel Fiol and Mariano Vald{\'e}s and Carlos Macaya and Jos{\'e} Ram{\'o}n Gonz{\'a}lez-Juanatey and Juan Cinca and Antoni Bay{\'e}s de Luna},
  journal={Journal of Cardiovascular Electrophysiology},
  year={2008},
  volume={19}
}
Introduction: Repolarization dynamics, reflecting adaptation of QT to changing heart rate, is considered a marker of unfavorable prognosis in patients with heart diseases. We aimed to evaluate the prognostic value of QT/RR slope in predicting total mortality (TM) and sudden death (SD) in patients with congestive heart failure (CHF). 
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TLDR
The present article reviews the literature data on the prognostic role of various Holter-based ECG parameters, with special emphasis to dynamic ECG risk markers--heart rate variability, heart rate turbulence, repolarization dynamics and variability--in predicting mortality, as well as different modes of death in patients with CHF.
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TLDR
Although predictive accuracy might be improved among cohorts with a higher likelihood of cardiovascular events, this would also affect the prevalence of abnormal parameters and their exclusions.
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TLDR
Why risk assessment is needed and the methods available to facilitate risk assessment, the rationale for applying these techniques, and the limitations of these techniques are reviewed.
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TLDR
In patients with diastolic HF older age, male gender, non-Caucasian ethnicity, history of coronary artery disease and atrial fibrillation are associated with poor prognosis, and Anemia and B-type natriuretic peptide are significant laboratory variable that predict mortality.
Predictive Value of Beat-to-Beat QT Variability Index Across the Continuum of Left Ventricular Dysfunction: Competing Risks of Noncardiac or Cardiovascular Death and Sudden or Nonsudden Cardiac Death
TLDR
Increased QTVI because of depressed heart rate variability predicts cardiovascular mortality and non-SCD but neither SCD nor extracardiac mortality in heart failure across the continuum of left ventricular dysfunction.
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