Prognostic Value of Perineural Invasion in Colorectal Cancer: A Meta-Analysis

  title={Prognostic Value of Perineural Invasion in Colorectal Cancer: A Meta-Analysis},
  author={Yuchong Yang and Xuanzhang Huang and Jing-xu Sun and P. P. Gao and Yongxi Song and Xiaowan Chen and Junhua Zhao and Zhenning Wang},
  journal={Journal of Gastrointestinal Surgery},
The prognostic value of perineural invasion (PNI) in colorectal cancer (CRC) does not reach a consensus. A comprehensive literature search for relevant reports published up to October 2014 was performed using the electronic databases: PubMed, Embase, and Web of Science. The pooled hazard ratio (HR) with 95 % confidence intervals (CI) was used to estimate the prognostic effects. Thirty-eight studies comprising 12,661 CRC patients were analyzed. Our results showed that PNI is significantly… CONTINUE READING
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