Prognostic Value of Loss of Heterozygosity around three Candidate Tumor Suppressor Genes on Chromosome 10q in Astrocytomas

@article{Terada2002PrognosticVO,
  title={Prognostic Value of Loss of Heterozygosity around three Candidate Tumor Suppressor Genes on Chromosome 10q in Astrocytomas},
  author={Kinya Terada and Takashi Tamiya and Shigeru Daido and Hirokazu Kambara and Hiroaki Tanaka and Yasuhiro Ono and Kengo Matsumoto and Sachio Ito and Mamoru Ouchida and Takashi Ohmoto and Kenji Shimizu},
  journal={Journal of Neuro-Oncology},
  year={2002},
  volume={58},
  pages={107-114}
}
We thoroughly examined loss of heterozygosity (LOH) around three candidate tumor suppressor genes on chromosome 10q to determine whether LOH of each tumor suppressor gene is associated with the previously defined clinical prognostic indices. We also examined whether LOH can help predict prognostic variables in astrocytomas. We selected samples from 40… CONTINUE READING