Prognostic Value of Clinical Variables at Presentation in Patients with Non-ST-Segment Elevation Acute Coronary Syndromes: Results of the Proyecto de Estudio del Pronóstico de la Angina (PEPA)

@article{deSa2002PrognosticVO,
  title={Prognostic Value of Clinical Variables at Presentation in Patients with Non-ST-Segment Elevation Acute Coronary Syndromes: Results of the Proyecto de Estudio del Pron{\'o}stico de la Angina (PEPA)},
  author={Esteban Lopez de Sa and Jos{\'e} Luis L{\'o}pez-Send{\'o}n and Ignasi Anguera and Armando Bethencourt and Xavier Bosch},
  journal={Medicine},
  year={2002},
  volume={81},
  pages={434-442}
}
Patients with suspected non-ST-segment elevation acute coronary syndromes (NSTEACS) constitute a heterogeneous population with variable outcomes. Risk stratification in this population of patients is difficult due to the complexity in patient risk profile. We conducted this study to characterize the value of clinical and electrocardiographic variables for risk stratification in an unselected population of consecutive patients with NSTEACS on admission. Thirty-five clinical and… 

[Clinical characteristics, prognosis, and variability in the management of non-ST-segment elevation acute coronary syndromes. Data from the PEPA registry].

Patients with non-ST-segment elevation acute coronary syndromes represent an heterogeneous group with a high incidence of complications, and Pharmacologic and, especially, invasive treatment varies widely in different hospitals.

[Inflammation markers and risk stratification in patients with acute coronary syndromes: design of the SIESTA Study (Systemic Inflammation Evaluation in Patients with non-ST segment elevation Acute coronary syndromes)].

The main objective of the SIESTA study is to assess the relative prognostic roles of C-reactive protein, fibrinogen, neopterin, interleukins 6, 8, 10 and 18, tumor necrosis factor, e-selectin, endothelin 1, tissue factor and serum creatine kinase-MB in UA/NSTEMI patients.

Magnitude and consequences of undertreatment of high-risk patients with non-ST segment elevation acute coronary syndromes: insights from the DESCARTES Registry

Class I recommended treatments were underused in high-risk patients in the DESCARTES registry and undertreatment was an independent predictor of death of patients with an acute coronary syndrome.

ISCHEMIC HEART DISEASE Emergency Room Risk Stratification of Patients With Chest Pain Without ST Segment Elevation

In patients with chest pain, the combination of clinical, electrocardiographic and biochemical data available on admission to the emergency service allows rapid prognostic stratification and early exercise testing is advisable for the final stratification of low risk patients.

Prognostic importance of physical examination for heart failure in non-ST-elevation acute coronary syndromes: the enduring value of Killip classification.

Kilip classification is a powerful independent predictor of all-cause mortality in patients with non-ST-elevation acute coronary syndromes and should receive particular attention in the initial assessment of these patients.

P Myocardial Infarction / Ischemia ew Risk Score for Patients With cute Chest Pain , Non – ST-Segment eviation , and Normal Troponin Concentrations Comparison With the TIMI Risk Score

A risk score derived from patients presenting with chest pain despite no ST-segment deviation or troponin elevation show a non-negligible rate of events at one year, which allows more accurate stratification than when using the TIMI risk score.
...

References

SHOWING 1-10 OF 37 REFERENCES

Clinical outcomes, risk stratification and practice patterns of unstable angina and myocardial infarction without ST elevation: Prospective Registry of Acute Ischaemic Syndromes in the UK (PRAIS-UK)

A review of treatment strategies of unstable angina and myocardial infarction without ST elevation is warranted in the U.K. to ensure that patients are receiving optimum treatments to reduce mortality and morbidity.

Predictors of outcome in patients with acute coronary syndromes without persistent ST-segment elevation. Results from an international trial of 9461 patients. The PURSUIT Investigators.

The occurrence of adverse events after presentation with acute coronary syndromes is affected by multiple factors and these factors should be considered in the clinical decision-making process.

Influence of race, sex, and age on management of unstable angina and non-Q-wave myocardial infarction: The TIMI III registry.

Among patients presenting with acute ischemic chest pain without persistent ST-segment elevation, blacks appeared to have less severe coronary disease, received revascularization less frequently, and had less recurrent ischemia compared with nonblacks, which suggests that more aggressive strategies should be directed to those patients with the greatest likelihood of adverse outcomes.

The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making.

In patients with UA/NSTEMI, the TIMI risk score is a simple prognostication scheme that categorizes a patient's risk of death and ischemic events and provides a basis for therapeutic decision making.

Risk stratification in unstable coronary artery disease. Additive value of troponin T determinations and pre-discharge exercise tests. FRISK Study Group.

In 963 patients, participating in a randomized study of low molecular weight heparin in unstable coronary artery disease and followed for 5 months, troponin T level and exercise test response were determined and both were independent predictors of prognosis.

PREDICT: A simple risk score for clinical severity and long-term prognosis after hospitalization for acute myocardial infarction or unstable angina: the Minnesota heart survey.

The simple PREDICT risk score was a powerful prognosticator of 6-year mortality after hospitalization and declined 32% between 1970 and 1990.