Prognostic Relevance of Tn Expression in Breast Cancer.

  title={Prognostic Relevance of Tn Expression in Breast Cancer.},
  author={Tsuchiya and H Kanno and Kawaguchi and Endo and Zhang and Ohtake and Kimijima},
  journal={Breast cancer},
  volume={6 3},
BACKGROUND: Abnormal glycosylation patterns have been recognized as a featureof carcinomaassociated mucins. The expression of the Tn antigen in breast cancer tissue was investigated to assess its prognostic relevance. METHODS: Formalin-fixed, paraffin-embedded materials from 219 patients with breast cancer were used. Immunohistochemical staining of the Tn antigen was retrospectively investigated and a lesion staining 10% or more was considered positive RESULTS: Tn antigen expression was present… CONTINUE READING