Prognostic Impact of TP 53 Mutations and P 53 Protein Overexpression in Supratentorial WHO Grade II Astrocytomas and Oligoastrocytomas 1


Purpose: The purpose of this study was to analyze retrospectively timing, frequency, and prognostic impact of TP53 mutations and P53 protein accumulation in supratentorial WHO grade II astrocytomas and oligoastrocytomas of adult patients. Experimental Design: We included 159 consecutively treated patients (1991–1998), and each tumor was screened for TP53… (More)

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