Prognostic Impact of Clinicopathological Features and Expression of Biomarkers Related to 18F-FDG Uptake in Esophageal Cancer

@article{Schreurs2014PrognosticIO,
  title={Prognostic Impact of Clinicopathological Features and Expression of Biomarkers Related to 18F-FDG Uptake in Esophageal Cancer},
  author={PhD L. M. A. Schreurs and PhD J. K. Smit and Kaloyan Pavlov and PhD B. B. Pultrum and PhD J. Pruim and PhD H. Groen and PhD H. Hollema and John Th. M. Plukker},
  journal={Annals of Surgical Oncology},
  year={2014},
  volume={21},
  pages={3751-3757}
}
To analyze the association between pretreatment 18-F-fluoro-deoxyglucose (FDG) uptake and characteristics of aggressive tumor biology in predicting outcome in esophageal cancer (EC). Tumor FDG-uptake was measured by maximum standardized uptake values (SUVmax) in 47 patients undergoing esophagectomy with curative intent. ROC analyses were used to predict an optimal SUVmax cutoff for survival. Expression of hexokinase-II (HK-II), glucose transporter I (GLUT-I), hypoxia inducible factor-1α (HIF-I… CONTINUE READING