Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: an institutional-based review.

@article{Dawood2010PrognosisOW,
  title={Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: an institutional-based review.},
  author={Shaheenah Dawood and Kristine R Broglio and Aman U. Buzdar and Gabriel N Hortobagyi and Sharon Hermes Giordano},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2010},
  volume={28 1},
  pages={92-8}
}
PURPOSE The purpose of this study was to determine whether trastuzumab improves prognosis of women with metastatic human epidermal growth factor receptor 2 (HER2)/neu -positive breast cancer beyond that of women with HER2/neu-negative disease. PATIENTS AND METHODS Two thousand ninety-one women with metastatic breast cancer diagnosed from 1991 to 2007, with known HER2/neu status and who had not received trastuzumab in the adjuvant setting, were identified. Disease was classified into the… CONTINUE READING
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