Prognosis of pediatric patients transplanted for Ph+ chronic myeloid leukemia in the period from 1989 to 2006 in the Czech Republic.

@article{Krl2008PrognosisOP,
  title={Prognosis of pediatric patients transplanted for Ph+ chronic myeloid leukemia in the period from 1989 to 2006 in the Czech Republic.},
  author={Ladislav Kr{\'o}l and Renata Form{\'a}nkov{\'a} and Petra Keslov{\'a} and Vladim{\'i}r V{\'a}vra and Zuzana Zemanova and Kyra Michalov{\'a} and Marie Dobrovoln{\'a} and Jana Moravcov{\'a} and Petr Kobylka and Eva Iva{\vs}kov{\'a} and Jana Navr{\'a}tilov{\'a} and Jan Star{\'y} and Petr Sedl{\'a}cek},
  journal={Neoplasma},
  year={2008},
  volume={55 2},
  pages={101-6}
}
Chronic myeloid leukemia (CML) is a myeloproliferative disorder caused by clonal proliferation of primitive hematopoietic stem cell. The median age at diagnosis is 55 to 60 years with less than 10% of patients younger 20 years. Incidence of CML in children in the Czech Republic is 0.106 cases/100 thousands per year. Here we report outcome of 38 pediatric patients (median age 12.5 years; range 1.8 - 17.3) with Ph-positive CML diagnosed between years 1989 to 2006. Primarily chronic phase of the… CONTINUE READING