Prognosis of oral pre-malignant lesions: significance of clinical, histopathological, and molecular biological characteristics.

@article{Reibel2003PrognosisOO,
  title={Prognosis of oral pre-malignant lesions: significance of clinical, histopathological, and molecular biological characteristics.},
  author={Jesper Reibel},
  journal={Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists},
  year={2003},
  volume={14 1},
  pages={47-62}
}
  • Jesper Reibel
  • Published 2003 in
    Critical reviews in oral biology and medicine…
The concept of a two-step process of cancer development in the oral mucosa, i.e., the initial presence of a precursor subsequently developing into cancer, is well-established. Oral leukoplakia is the best-known precursor lesion. The evidence that oral leukoplakias are pre-malignant is mainly derived from follow-up studies showing that between < 1 and 18% of oral pre-malignant lesions will develop into oral cancer; it has been shown that certain clinical sub-types of leukoplakia are at a higher… CONTINUE READING
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